SRI antibody (AA 50-100)

Catalog No. ABIN372264

This anti-SRI antibody is a Rabbit Polyclonal antibody detecting SRI in WB and IHC (p). Suitable for Human, Mouse, Rat, Horse, Dog, Cow, Monkey, Opossum, Xenopus laevis, Chimpanzee and Chicken.

Quick Overview for SRI antibody (AA 50-100) (ABIN372264)

Target: SRI (Sorcin (SRI))

Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Monkey, Opossum, Xenopus laevis, Chimpanzee, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SRI Antibody

Binding Specificity: AA 50-100

Specificity: This antibody recognizes SORCIN (SRI).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chimpanzee, Chicken, Dog (Canine), Xenopus, Horse, Monkey, Mouse, Opossum and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 50-100 of human Sorcin.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SRI

Target: SRI (Sorcin (SRI))

Alternative Name: Sorcin / SRI

Background: Sorcin (SR1) is a Ca2+-binding protein first identified in multidrug-resistant cells. This protein is widely distributed in mammalian tissues, including heart and skeletal muscle. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac SR and co-localizes with brain ryanodine receptors in rat brain caudate-putamen nucleus.

Molecular Weight: 22 kDa

Gene ID: 6717

NCBI Accession: NP_003121

UniProt: P30626

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity