SRI antibody (AA 50-100)

Catalog No. ABIN372264

Product Details anti-SRI Antibody

Target: SRI (Sorcin (SRI))

Binding Specificity: AA 50-100

Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Monkey, Opossum, Xenopus laevis, Chimpanzee, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes SORCIN (SRI).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chimpanzee, Chicken, Dog (Canine), Xenopus, Horse, Monkey, Mouse, Opossum and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 50-100 of human Sorcin.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SRI

Target: SRI (Sorcin (SRI))

Alternative Name: Sorcin / SRI (SRI Products)

Background: Sorcin (SR1) is a Ca2+-binding protein first identified in multidrug-resistant cells. This protein is widely distributed in mammalian tissues, including heart and skeletal muscle. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac SR and co-localizes with brain ryanodine receptors in rat brain caudate-putamen nucleus.

Molecular Weight: 22 kDa

Gene ID: 6717

NCBI Accession: NP_003121

UniProt: P30626

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity