NEFH antibody

Catalog No. ABIN372672

This anti-NEFH antibody is a Chicken Polyclonal antibody detecting NEFH in WB, IF and IHC (fro). Suitable for Human, Rat, Mouse and Chicken.

Quick Overview for NEFH antibody (ABIN372672)

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Reactivity: Human, Rat, Mouse, Chicken

Host: Chicken

Clonality: Polyclonal

Conjugate: This NEFH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NEFH Antibody

Cross-Reactivity (Details): Species reactivity (tested):Human, Chicken, Mouse and Rat.

Purification: Ig Fraction

Immunogen: Purified bovine NF-H

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1/50,000. Immunohistochemistry. Immunofluorescence: 1/25,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for NEFH

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Alternative Name: Neurofilament H (200 kD)

Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (Ref.1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (Ref.2) and Alzheimer's disease (Ref.3).Synonyms: (Neuronal Marker), 200 kDa neurofilament protein, KIAA0845, NEFH, NF-H, NFH, Neurofilament triplet H protein, heavy polypeptide

Gene ID: 10116

UniProt: P16884