RAPSN antibody (C-Term)
Quick Overview for RAPSN antibody (C-Term) (ABIN372886)
Target
See all RAPSN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- This antibody reacts to Receptor-associated Protein Of The Synapse, 43 kDa (RAPSN).
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Cross-Reactivity (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography
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Immunogen
- Synthetic peptide
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Isotype
- IgG
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Application Notes
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Immunohistochemistry on paraffin sections: 10 - 20 μg/mL. Western blot: 1 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.01 % sodium azide and 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))
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Alternative Name
- RAPSN / RNF205
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Background
- Nicotinic acetylcholine receptors (AChRs) are organized into high-density postsynaptic clusters at the motor endplate that are critical for efficient synaptic transmission. The organization of AChRs is carried out by the 43 kDa cytoplasmic protein rapsyn. Studies have indicated that mutations which impair the activity of rapsyn can lead to the formation of congenital myasthenic syndrome (CMS). CMS is characterized by poor development of the postsynaptic region.Synonyms: 43 kDa postsynaptic protein, 43 kDa receptor-associated protein of the synapse, Acetylcholine receptor-associated 43 kDa protein, RAPsyn, RING finger protein 205
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Gene ID
- 5913
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NCBI Accession
- NP_005046
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UniProt
- Q13702
Target
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