LRRC7 antibody (N-Term)

Catalog No. ABIN372984

Product Details anti-LRRC7 Antibody

Target: LRRC7 (Leucine Rich Repeat Containing 7 (LRRC7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts to Leucine Rich Repeat Containing 7 (LRRC7).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 5 μg/mL. Western blot: 1 μg/mL. ELISA: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.01 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for LRRC7

Target: LRRC7 (Leucine Rich Repeat Containing 7 (LRRC7))

Alternative Name: LRRC7 (LRRC7 Products)

Background: The attachment of the lamins to the inner nuclear membrane appears to occur through their association with 4 related integral membrane proteins called Lamin Associated Polypeptides (LAPs). LAP 1A, 1B & 1C share a high degree of sequence homology while LAP 2 is distinct from the others. LAP1 is a brain specific protein that may be involved in the organization of synaptic cell-cell contacts. LAP1 interacts with CAMKII and CTNND2/Catenin delta-2 and forms a complex with N-cadherin through CTNND2. There are three named isforms produced by alternative splicing.Synonyms: Densin-180, KIAA1365, LAP1, LRRC7, Leucine-rich repeat-containing protein 7

Gene ID: 57554

NCBI Accession: NP_065845

UniProt: Q96NW7

Pathways: Synaptic Membrane