SUPT16H antibody (Internal Region)

Catalog No. ABIN374777

The Goat Polyclonal anti-SUPT16H antibody has been validated for WB. It is suitable to detect SUPT16H in samples from Human.

Quick Overview for SUPT16H antibody (Internal Region) (ABIN374777)

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This SUPT16H antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SUPT16H Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to FACT / SUPT16H.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Porcine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-DLTNKEGKKPEEK, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SUPT16H

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Alternative Name: SUPT16H / FACT140

Background: SUPT16H plays a role in general transcription, it has positive and negative effects on gene expression. Required for the appropriate synthesis during heat shock. Required for continued expression of cyclin genes that determine the passage through start during cell cycle control. it may act as an acidic activator. Its function is probably related to other spt genes.Synonyms: Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTp140, Facilitates chromatin transcription complex subunit SPT16

Gene ID: 11198

NCBI Accession: NP_009123

UniProt: Q9Y5B9

Pathways: Chromatin Binding