SENP8 antibody (N-Term)

Catalog No. ABIN388073

The Rabbit Polyclonal anti-SENP8 antibody has been validated for WB. It is suitable to detect SENP8 in samples from Human and Mouse.

Quick Overview for SENP8 antibody (N-Term) (ABIN388073)

Target: SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP8 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB2330

Product Details anti-SENP8 Antibody

Binding Specificity: AA 4-35, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SENP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-35 amino acids from the N-terminal region of human SENP8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SENP8

Target: SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))

Alternative Name: SENP8

Background: NEDD8 is a ubiquitin-like protein that becomes conjugated to the cullin subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. SENP8 is a protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.

Molecular Weight: 24107

Gene ID: 123228

NCBI Accession: NP_001159812, NP_001165580, NP_001165581, NP_001165582, NP_660205

UniProt: Q96LD8