Ubiquilin 1 antibody (C-Term)

Catalog No. ABIN388964

The Rabbit Polyclonal anti-Ubiquilin 1 antibody has been validated for WB. It is suitable to detect Ubiquilin 1 in samples from Human.

Quick Overview for Ubiquilin 1 antibody (C-Term) (ABIN388964)

Target: Ubiquilin 1 (UBQLN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB4549

Product Details anti-Ubiquilin 1 Antibody

Binding Specificity: AA 515-545, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Dsk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 515-545 amino acids from the C-terminal region of human Dsk2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Ubiquilin 1

Target: Ubiquilin 1 (UBQLN1)

Alternative Name: Dsk2

Background: Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome, it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.

Molecular Weight: 65696

Gene ID: 29978

NCBI Accession: NP_038472

UniProt: Q9UHD9