Epsin 2 antibody (N-Term)

Catalog No. ABIN388977

This anti-Epsin 2 antibody is a Rabbit Polyclonal antibody detecting Epsin 2 in WB and IHC (p). Suitable for Human and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for Epsin 2 antibody (N-Term) (ABIN388977)

Target: Epsin 2 (EPN2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epsin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB4610

Product Details anti-Epsin 2 Antibody

Binding Specificity: AA 6-36, N-Term

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Epsin2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human Epsin2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Epsin 2 antibody (ABIN388977)

Bhattacharyya, Rainey, Arya, Mohapatra, Mushtaq, Dutta, George, Storck, McComb, Muirhead, Todd, Gould, Datta, Gelineau-van Waes, Band, Band: "Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development." in: Scientific reports, Vol. 6, pp. 20727, (2016) (PubMed).

Target Details for Epsin 2

Target: Epsin 2 (EPN2)

Alternative Name: Epsin2

Background: Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.

Molecular Weight: 68482

Gene ID: 22905

NCBI Accession: NP_001096134, NP_055779, NP_683723

UniProt: O95208

Pathways: EGFR Downregulation