KHSRP antibody (N-Term)

Catalog No. ABIN390852

This anti-KHSRP antibody is a Rabbit Polyclonal antibody detecting KHSRP in WB, IF and IHC (p). Suitable for Human.

Quick Overview for KHSRP antibody (N-Term) (ABIN390852)

Target: KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHSRP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB17895

Product Details anti-KHSRP Antibody

Binding Specificity: AA 94-122, N-Term

Predicted Reactivity: C

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KHSRP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human KHSRP.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for KHSRP

Target: KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))

Alternative Name: KHSRP

Background: KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). It is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) and activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Molecular Weight: 73115

Gene ID: 8570

NCBI Accession: NP_003676

UniProt: Q92945