GIT1 antibody (AA 487-517)

Catalog No. ABIN391615

This Rabbit Polyclonal antibody specifically detects GIT1 in WB and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for GIT1 antibody (AA 487-517) (ABIN391615)

Target: GIT1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15373

Product Details anti-GIT1 Antibody

Binding Specificity: AA 487-517

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-GIT1 antibody (ABIN391615)

Aslan, Baker, Loren, Haley, Itakura, Pang, Greenberg, David, Manser, Chernoff, McCarty: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." in: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).

Target Details for GIT1

Target: GIT1

Alternative Name: GIT1

Background: GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.

Molecular Weight: 84341

Gene ID: 28964

NCBI Accession: NP_001078923, NP_054749

UniProt: Q9Y2X7