AARS antibody (N-Term)

Catalog No. ABIN2841658

This Rabbit Polyclonal antibody specifically detects AARS in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for AARS antibody (N-Term) (ABIN2841658)

Target: AARS (Alanyl tRNA Synthetase (AARS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14611

Product Details anti-AARS Antibody

Binding Specificity: AA 61-91, N-Term

Predicted Reactivity: E, D, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AlaRS (AARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-91 amino acids from the N-terminal region of human AlaRS (AARS).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for AARS

Target: AARS (Alanyl tRNA Synthetase (AARS))

Alternative Name: AlaRS (AARS)

Background: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases,of the class II enzymes.Class II tRNA synthases evolved early in evolution and are highly conserved.This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein.tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons.They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

Molecular Weight: 106810

Gene ID: 16

NCBI Accession: NP_001596

UniProt: P49588