RSL1D1 antibody (Internal Region)

Catalog No. ABIN401398

This Rabbit Polyclonal antibody specifically detects RSL1D1 in WB, IF, IP and EIA. It exhibits reactivity toward Human.

Quick Overview for RSL1D1 antibody (Internal Region) (ABIN401398)

Target: RSL1D1 (Ribosomal L1 Domain Containing 1 (RSL1D1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSL1D1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Product Details anti-RSL1D1 Antibody

Binding Specificity: Internal Region

Specificity: This antibody is specific for PBK1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to an internal sequence of human PBK1

Isotype: IgG

Application Details

Application Notes: ELISA: 1/2,500 - 1/10,000. WESTWestern Blot: 1/500 - 1/2,000. Immunoprecipitation: 1/100. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.1 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for RSL1D1

Target: RSL1D1 (Ribosomal L1 Domain Containing 1 (RSL1D1))

Alternative Name: RSL1D1

Background: PBK1 protein (also known as Ribosomal L1 domain-containing protein 1, cellular senescence-inhibited gene protein, and CATX-11) was isolated from highly invasive first trimester trophoblast cells and has been proposed to regulate their naturally occurring invasive behavior (Huch et al., 1998). PBK1 was also found to be over-expressed in non-small-cell lung cancer (NSCLC) cells (Petroziello et al., 2004). A recent study suggests that PBK1 may up-regulate the urokinase-type plasminogen activator (uPA) gene, which plays an important role in cellular matrix degradation and activation of other protease systems involved in cell invasion (Tong et al., 2005). PBK1 shows a nuclear and nucleolar localization.Synonyms: CATX-11, CSIG, Cellular senescence-inhibited gene protein, PBK1, Ribosomal L1 domain-containing protein 1

Gene ID: 26156

NCBI Accession: NP_056474

UniProt: O76021