alpha Fetoprotein antibody (HRP)

Catalog No. ABIN452557

This Mouse Monoclonal antibody specifically detects alpha Fetoprotein in EIA and ELISA (Detection). It exhibits reactivity toward Human.

Quick Overview for alpha Fetoprotein antibody (HRP) (ABIN452557)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Fetoprotein antibody is conjugated to HRP

Application: Enzyme Immunoassay (EIA), ELISA (Detection)

Clone: AFP-Y2

Product Details anti-alpha Fetoprotein Antibody (HRP)

Specificity: This AFP-Y2 antibody react with AFP. No detectable cross reaction with Human normal serum proteins.

Characteristics: Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP

Purification: Affinity chromatography

Immunogen: Recombinant partial human PML

Isotype: IgG1

Application Details

Application Notes: EIA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M PBS, pH 7.2 with 50 % Glycerol

Storage: -20 °C

Storage Comment: Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Background: Alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP

Gene ID: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process