HSV-1+2 gB antibody

Catalog No. ABIN457436

The Mouse Monoclonal anti-HSV-1+2 gB antibody has been validated for ICC and ELISA. It is suitable to detect HSV-1+2 gB in samples from Herpes Simplex Virus (HSV). There are 4+ publications available.

Quick Overview for HSV-1+2 gB antibody (ABIN457436)

Target: HSV-1+2 gB (HSV1/2 gB) (Herpes Simplex Virus Type 1/2, Glycoprotein B (HSV1/2 gB))

Reactivity: Herpes Simplex Virus (HSV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSV-1+2 gB antibody is un-conjugated

Application: Immunocytochemistry (ICC), ELISA

Clone: T111

Product Details anti-HSV-1+2 gB Antibody

Purpose: Anti-HSV-1/HSV-2 glycoprotein B Purified

Specificity: The antibody T111 recognizes gB antigen of both HSV1 and HSV2 (Herpes Simplex Virus type 1 and 2), a dsDNA virus, member of Herpesviridae family.

Cross-Reactivity (Details): HSV

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Exctract of HSV-1 infected VERO (green monkey kidney) cells.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

References for anti-HSV-1+2 gB antibody (ABIN457436)

Mboumba Bouassa, Péré, Gubavu, Prazuck, Jenabian, Veyer, Meye, Touzé, Bélec: "Serum and cervicovaginal IgG immune responses against α7 and α9 HPV in non-vaccinated women at risk for cervical cancer: Implication for catch-up prophylactic HPV vaccination." in: PLoS ONE, Vol. 15, Issue 5, pp. e0233084, (2020) (PubMed).

Bystrická, Zatovicová, Petríková, Soláriková, Russ, Ziegler: "Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay." in: Acta virologica, Vol. 43, Issue 6, pp. 399-402, (2000) (PubMed).

Bystrická, Petríková, Zatovicová, Soláriková, Kostolanský, Mucha, Russ: "Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection." in: Acta virologica, Vol. 41, Issue 1, pp. 5-12, (1997) (PubMed).

Bystrická, Vancíková, Kasalová, Rajcáni, Kostál, Murányiová, Poláková, Russ: "Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2." in: Acta virologica, Vol. 35, Issue 2, pp. 152-64, (1991) (PubMed).

Target Details for HSV-1+2 gB

Target: HSV-1+2 gB (HSV1/2 gB) (Herpes Simplex Virus Type 1/2, Glycoprotein B (HSV1/2 gB))

Alternative Name: HSV-1/HSV-2 glycoprotein B

Target Type: Viral Protein

Background: Envelope glycoprotein B,Herpes simplex virus (HSV) is a virus that manifests itself in two common viral infections. There are actually two types of herpes simplex virus, HSV1 and HSV2. These are very similar in many ways, and both can cause either oral herpes or genital herpes. HSV1 - most commonly develops into oral herpes infecting the lips (fever blisters or cold sores). HSV1 can also infect the genital area causing sores to develop. HSV2 - generally infects the genital area (genital herpes), however, HSV2 can also infect the mouth.,HSVGB, HSV-1 gB, HSV-2 gB

Gene ID: 24271469

UniProt: P10211