MHC Class II I-A antibody (FITC)

Catalog No. ABIN479312

The Mouse Monoclonal anti-MHC Class II I-A antibody has been validated for FACS. It is suitable to detect MHC Class II I-A in samples from Rat.

Quick Overview for MHC Class II I-A antibody (FITC) (ABIN479312)

Target: MHC Class II I-A

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This MHC Class II I-A antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-MHC Class II I-A Antibody (FITC)

Specificity: Recognizes a polymorphic determinant of rat Ia antigen present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains. The antibody cross-reacts with mouse strains (MHC haplotypes b and s) and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. It recognizes la antigens on B-cells, dendritic cells and certain epithelial cells. It is particularly useful for distinguishing la positive cells from different rat strains, e. g. for recognizing cells of donor origin in bone marrow reconstituted radiation chimeras (3,4.

Purification: Purified

Immunogen: Rat thymocyte membrane glycoproteins.

Type of Immunogen: Membrane extract

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for MHC Class II I-A

Target: MHC Class II I-A