CXCR2 antibody (pSer347)

Catalog No. ABIN482281

This Rabbit Polyclonal antibody specifically detects CXCR2 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CXCR2 antibody (pSer347) (ABIN482281)

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CXCR2 Antibody

Binding Specificity: AA 311-360, pSer347

Specificity:

IL-8R beta/CDw128 beta (Phospho-Ser347) Antibody detects endogenous levels of IL-8R beta/CDw128 beta only when phosphorylated at Ser347.

PhosphorylationH:S347 M:S346

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-8R beta/CDw128 beta around the phosphorylation site of Ser347.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.846 (NCBI Gene Symbol: CXCR2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Alternative Name: IL-8R beta/cdw128 beta

Background:

Synonyms: High affinity interleukin-8 receptor B, IL-8R B, CXCR-2, GRO/MGSA receptor, IL-8 receptor type 2, CD182 antigen, CDw128b, IL8RB, CXCR2

NCBI Gene Symbol: CXCR2

Molecular Weight: 40 kDa

Gene ID: 3579

OMIM: 146928

UniProt: P25025

Pathways: cAMP Metabolic Process