AQP11 antibody (N-Term)

Catalog No. ABIN4886472

This anti-AQP11 antibody is a Rabbit Polyclonal antibody detecting AQP11 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for AQP11 antibody (N-Term) (ABIN4886472)

Target: AQP11 (Aquaporin 11 (AQP11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AQP11 Antibody

Binding Specificity: AA 35-70, N-Term

Purpose: Anti-AQP11 Antibody Picoband®

Sequence: ARQQLHRPVA HAFVLEFLAT FQLCCCTHEL QLLSEQ

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-AQP11 Antibody Picoband® (ABIN4886472). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human AQP11, different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Morishita, Y., Matsuzaki, T., Hara-chikuma, M., Andoo, A., Shimono, M., Matsuki, A., Kobayashi, K., Ikeda, M., Yamamoto, T., Verkman, A., Kusano, E., Ookawara, S., Takata, K., Sasaki, S., Ishibashi, K.Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Molec. Cell. Biol. 25: 7770-7779, 2005.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for AQP11

Target: AQP11 (Aquaporin 11 (AQP11))

Alternative Name: AQP11

Background:

Synonyms: Aquaporin-11,AQP-11,AQP11,AQPX1,PSEC0027,

Tissue Specificity: Liver. .

Background: AQP11 has a unique asparagine-proline-alanine (NPA) box distinct from those of other AQPs, suggesting a different pore structure and function. Using Northern blot analysis, they detected highest expression of mouse Aqp11 in testis, followed by liver and kidney. Expression was much weaker in heart, brain, and muscle. Western blot analysis of mouse kidney membrane fractions detected Aqp11 at an apparent molecular mass of 26 kD, lower than the calculated molecular mass of 30 kD. Immunohistochemical analysis localized Aqp11 to mouse renal proximal tubule cells, where it showed a perinuclear distribution. Fluorescence-tagged Aqp11 localized with an endoplasmic reticulum marker.

Molecular Weight: 30 kDa

Gene ID: 282679