BMP15 antibody (AA 268-392)

Catalog No. ABIN4886488

This Rabbit Polyclonal antibody specifically detects BMP15 in WB. It exhibits reactivity toward Human.

Quick Overview for BMP15 antibody (AA 268-392) (ABIN4886488)

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMP15 Antibody

Binding Specificity: AA 268-392

Purpose: Anti-BMP15 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-BMP15 Antibody Picoband® (ABIN4886488). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human BMP15 recombinant protein (Position: Q268-R392). Human BMP15 shares 69.6% amino acid (aa) sequence identity with mouse BMP15.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Dube JL, Wang P, Elvin J, Lyons KM, Celeste AJ, Matzuk MM (Feb 1999). "The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes". Mol Endocrinol 12 (12): 1809-17. 2. Persani, L., Rossetti, R., Di Pasquale, E., Cacciatore, C., Fabre, S. (2014). "The fundamental role of bone morphogenetic protein 15 in ovarian function and its involvement in female fertility disorders". Human Reproduction Update 20 (6): 869-883.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for BMP15

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Alternative Name: BMP15

Background:

Synonyms: Bone morphogenetic protein 15,BMP-15,Growth/differentiation factor 9B,GDF-9B,BMP15,GDF9B,

Tissue Specificity: Ubiquitous. Widespread in normal smooth muscle tissue and neurons. .

Background: Bone morphogenetic protein 15 is a protein that in humans is encoded by the BMP15 gene. It's mainly involved in folliculogenesis. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.

Molecular Weight: 56 kDa

Gene ID: 9210

UniProt: O95972