SYN2 antibody (AA 497-582)

Catalog No. ABIN4886735

The Rabbit Polyclonal anti-SYN2 antibody has been validated for WB. It is suitable to detect SYN2 in samples from Mouse, Human and Rat.

Quick Overview for SYN2 antibody (AA 497-582) (ABIN4886735)

Target: SYN2 (Synapsin II (SYN2))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SYN2 Antibody

Binding Specificity: AA 497-582

Purpose: Anti-Synapsin II/SYN2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Synapsin II/SYN2 Antibody Picoband® (ABIN4886735). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1% and 89.7% amino acid (aa) sequence identity with mouse and rat Synapsin II, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: SYN2 synapsin II". 2. Li L, Chin LS, Greengard P, Copeland NG, Gilbert DJ, Jenkins NA (July 1995). "Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6". Genomics 28 (2): 365-6.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for SYN2

Target: SYN2 (Synapsin II (SYN2))

Alternative Name: SYN2

Background:

Synonyms: Synapsin-2,Synapsin II,SYN2,

Tissue Specificity: Central and peripheral nervous systems.

Background: Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite ion.

Molecular Weight: 52, 70 kDa

Gene ID: 6854

UniProt: Q92777