Streptococcus Oralis antibody
Reactivity: Streptococcus
CLSM, ELISA, FACS
Host: Rabbit
Polyclonal
unconjugated
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- Target
- Streptococcus Oralis
- Reactivity
- Streptococcus
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Confocal Laser Scanning Microscopy (CLSM), ELISA, Flow Cytometry (FACS)
- Specificity
- Streptococcus oralis, not crossreact against S.mutans ATCC 25175, P.gingivalis ATCC 33277, F.nucleatum ATCC 25586 [
- Characteristics
- S. oralis is a gram positive, non-motile, α-haemolytic bacterium that form chains of cocci. Streptococcus oralis is a commensal bacteria and is found in the human oral cavity [1]. S. oralis is a component of the normal human oral microbiota, and is capable of opportunistic pathogenicity. Once regarded as a minor opportunistic pathogen, S. oralis is now considered a significant pathogen that affects immunocompromised individuals and those with hematological malignancy (cancers that affect the blood). In these individuals S. oralis is known to create such complications as bacterial endocarditis, adult respiratory distress syndrome and streptococcal shock [1]. S. oralis is related to S. pneumoniae a common case of otitis media, septicemia, pneumonia, and meningitis in children that results in a significant mortality rate throughout the world [2]. S. oralis is known to be one of the first bacteria to begin to form the plaque biofilm. Research shows that the S. oralis is able to interact with Porphyromonas gingivalis, which is considered to be one of the leading causes of periodontal disease. Periodontal disease is considered the most common disease affecting the human oral cavity [3]. Interesting facts S. oralis has only been reported to cause meningitis in cases where dental work was recently performed [4]. S. oralis is also seeing use as a probiotic to help support a healthy oral cavity. The strain used as the probiotic is modified, and it helps to aid in restoring the mouth with good bacteria and helping to keep out bacteria that degenerate oral health. To do this, S. oralis colonizes sites around teeth such as the gums, and competes with other bacteria
- Purification
- Polyclonal immunoglobulins purified by protein A affinity chromatography
- Immunogen
- S. oralis ATCC 9811 1010 cells inactivated in glutaraldehyde 2.5%v/v
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol. Neutral pH.
- Storage
- 4 °C
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- Target
- Streptococcus Oralis
- Target Type
- Bacteria
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