FOXO antibody (N-Term)
This Rabbit Polyclonal antibody specifically detects FOXO in ELISA and WB. It exhibits reactivity toward Drosophila melanogaster.
Catalog No. ABIN4889143
Quick Overview for FOXO antibody (N-Term) (ABIN4889143)
Target
See all FOXO Antibodies
FOXO
(Forkhead Box, Sub-Group O (FOXO))
Reactivity
Drosophila melanogaster
Host
Rabbit
Clonality
Polyclonal
Conjugate
This FOXO antibody is un-conjugated
Application
ELISA, Western Blotting (WB)
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Binding Specificity
- N-Term
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Specificity
- Reacts with the Drosophila melanogaster dFOXO protein
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Purification
- Purified (protein A)
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Immunogen
- Synthetic peptide derived from Nter domain of the Drosophila dFOXO protein.
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:2000) -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Must be reconstituted in distilled water.
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Concentration
- 1 mg/mL
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Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
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Storage
- 4 °C/-20 °C
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Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Expiry Date
- 24 months
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- FOXO (Forkhead Box, Sub-Group O (FOXO))
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Alternative Name
- Forkhead Box Protein O (dFOXO)
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Background
- Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.
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Gene ID
- 41709
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UniProt
- Q95V55
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Pathways
- Cellular Glucan Metabolic Process, Regulation of Cell Size
Target
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