ATG7 antibody

Catalog No. ABIN4901029

Product Details anti-ATG7 Antibody

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: ATG7 is a protein encoded by the ATG7 gene which is approximately 77,9 kDa. ATG7 is localised to the cytoplasm. It is involved in the autophagy pathway, class I MHC mediated antigen processing and presentation, the HIV life cycle and oncogenic MAPK signalling. It is an E1-like activating enzyme that is essential for autophagy and transport from the cytoplasm to the vacuole. It is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. ATG7 is expressed in the nervous system, liver, kidney, intestine and lung. STJ98914 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous ATG7 protein.

Specificity: The antibody detects endogenous ATG7 protein.

Characteristics: Mouse Monoclonal to ATG7.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant peptide derived from ATG7.

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Comment:

Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Alternative Name: ATG7 (ATG7 Products)

Molecular Weight: 78kDa

Gene ID: 10533

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy