ATG7 antibody

Catalog No. ABIN4901029

This Mouse Monoclonal antibody specifically detects ATG7 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATG7 antibody (ABIN4901029)

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ATG7 Antibody

Purpose: ATG7 is a protein encoded by the ATG7 gene which is approximately 77,9 kDa. ATG7 is localised to the cytoplasm. It is involved in the autophagy pathway, class I MHC mediated antigen processing and presentation, the HIV life cycle and oncogenic MAPK signalling. It is an E1-like activating enzyme that is essential for autophagy and transport from the cytoplasm to the vacuole. It is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. ATG7 is expressed in the nervous system, liver, kidney, intestine and lung. STJ98914 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous ATG7 protein.

Specificity: The antibody detects endogenous ATG7 protein.

Characteristics: Mouse Monoclonal to ATG7.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant peptide derived from ATG7.

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Comment:

Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Alternative Name: ATG7

Molecular Weight: 78kDa

Gene ID: 10533

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy