Gelsolin antibody

Catalog No. ABIN4910400

This anti-Gelsolin antibody is a Mouse Monoclonal antibody detecting Gelsolin in WB. Suitable for Human.

Quick Overview for Gelsolin antibody (ABIN4910400)

Target: Gelsolin (GSN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 8T1

Product Details anti-Gelsolin Antibody

Cross-Reactivity: Human

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This GSN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.

Isotype: IgM

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GSN

Background:

Synonyms: ADF, AGEL, Gelsolin, Actin-depolymerizing factor, Brevin, GSN

Background: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Gene ID: 2934

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy