Lectin antibody

Catalog No. ABIN492365

The Mouse Monoclonal anti- antibody has been validated for EIA. It is suitable to detect in samples from Mistletoe.

Quick Overview for Lectin antibody (ABIN492365)

Target: Lectin

Reactivity: Mistletoe

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 2G8-F7

Product Details

Purification: Purified

Immunogen: Recombinant Mistletoe Lectin

Isotype: IgM

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in aqua bidest to 1 mg/mL

Buffer: PBS, pH 7.4

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details

Target: Lectin

Background: Mistletoe lectin I (ML-I) is a type II ribosome-inactivating protein, which inhibits the protein biosynthesis at the ribosomal level. ML-I is composed of a catalytically active A-chain with rRNA N-glycosidase activity and a B-chain with carbohydrate binding specificities. Using comparative solid-phase binding assays along with electrospray ionization tandem mass spectrometry, ML-I was shown to preferentially bind to terminally α2-6-sialylated neolacto series gangliosides from human granulocytes.Researchers across Europe (centres include Moscow, Berlin and London) have been investigating what specific properties of Viscum album could affect cancer cells. They have confirmed that some chemicals in European mistletoe can have anticancer properties. These properties are linked to various cytotoxic and immuno-modulatory compounds found in mistletoe, mainly the chemicals known as Viscotoxins and Mistletoe Lectins.