SUMO2 antibody (N-Term)

Catalog No. ABIN492386

The Mouse Monoclonal anti-SUMO2 antibody has been validated for WB, IF, IHC (p) and EIA. It is suitable to detect SUMO2 in samples from Human.

Quick Overview for SUMO2 antibody (N-Term) (ABIN492386)

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SUMO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: AT10F1

Product Details anti-SUMO2 Antibody

Binding Specificity: AA 1-93, N-Term

Specificity: The antibody recognizes human SUMO2/3. Other species not tested.

Characteristics: Synonyms: SUMO-2, SMT3B, SMT3H2, HSMT3, Sentrin-2, SUMO-3, SMT3 homolog 1, SMT3H1, Smallubiquitin-like modifier

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human SUMO2 (1-93aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1: 250 - 1: 500). Immunofluorescence (1: 250 - 1: 500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Alternative Name: SUMO2

Background: SUMO (small ubiquitin-related modifier) is the best-characterized member of a growing family of ubiquitin-related proteins. 8-11 kDa that covalently modify various intracellular proteins. It resembles ubiquitin in its structure, its ability to be ligated to other proteins. SUMO regulates cellular function of a variety of target proteins. SUMO proteins are expressed as their precursor forms. Cleavage of the residues after the 'GG' region of these precursors by SUMO-specific proteases in maturation is a prerequisite for subsequent sumoylation. Notably, SUMO2 and SUMO3 precursors have 96 % sequence identity, and recent studies have shown protein substrates conjugated with SUMO2 or SUMO3 have similar, if not identical, biological consequences.Synonyms: HSMT3, SMT3 homolog 1, SMT3B, SMT3H1, SMT3H2, SUMO-2, SUMO-3, Sentrin-2, Small ubiquitin-like modifier

Gene ID: 6613

UniProt: P61956

Pathways: Methionine Biosynthetic Process