Dityrosine antibody
(1 reference)-
- Target See all Dityrosine (DT) products
- Dityrosine (DT)
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Dityrosine antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein A Chromatography
- Immunogen
- 3-(p-hydroxyphenyl) propionic acid dimer KLH-conjugated
- Clone
- 1C3
- Isotype
- IgG2a
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anti-Dityrosine (DT) antibody
DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 unconjugated
anti-Dityrosine (DT) antibody (HRP)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 HRP
anti-Dityrosine (DT) antibody (FITC)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 FITC
anti-Dityrosine (DT) antibody (Biotin)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 Biotin
anti-Dityrosine (DT) antibody (PE)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 PE
anti-Dityrosine (DT) antibody (PerCP)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 PerCP
anti-Dityrosine (DT) antibody (APC)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 APC
anti-Dityrosine (DT) antibody (Atto 488)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 Atto 488
anti-Dityrosine (DT) antibody (Atto 594)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 Atto 594
anti-Dityrosine (DT) antibody (Atto 390)DT WB, ELISA, ICC, IF, FACS Host: Mouse Monoclonal 10A6 Atto 390
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- Application Notes
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ELISA (Ref.1,2)Western bLot (Ref.3,5)Immunohistochemistry on Paraffin Sections (Ref.4).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore in 200 μL aqua bidest to 0.1 mg/mL
- Storage
- -20 °C
- Storage Comment
- Store the antibody at -20 °CAfter reconstitution, store as frozen aliquotsAvoid repeated freezing and thawingShelf life: One year from despatch.
- Expiry Date
- 12 months
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: "Dietary oxidized tyrosine (O-Tyr) stimulates TGF-β1-induced extracellular matrix production via the JNK/p38 signaling pathway in rat kidneys." in: Amino acids, Vol. 49, Issue 2, pp. 241-260, (2018) (PubMed).
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: "Dietary oxidized tyrosine (O-Tyr) stimulates TGF-β1-induced extracellular matrix production via the JNK/p38 signaling pathway in rat kidneys." in: Amino acids, Vol. 49, Issue 2, pp. 241-260, (2018) (PubMed).
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- Target
- Dityrosine (DT)
- Alternative Name
- Dityrosine / DT (DT Products)
- Target Type
- Dipeptide
- Background
- Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. DT have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.
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