FTL antibody (AA 38-165)

Catalog No. ABIN4949673

This Mouse Monoclonal antibody specifically detects FTL in IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FTL antibody (AA 38-165) (ABIN4949673)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FTL-1389

Product Details anti-FTL Antibody

Binding Specificity: AA 38-165

Purification: Protein G affinity chromatography

Immunogen: Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Ferritin Light Chain antibody should be determined by the researcher.\. FACS: 0.1-0.2 μg/10^6 cells,IF: 0.1-0.2 μg/mL,IHC (FFPE): 0.1-0.2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Ferritin Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: Ferritin (light chain) / FTL1

Background: The FTL gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. This gene has multiple pseudogenes.

Although ferritin light chain has no ferroxidase activity, the light chain may be responsible for the electron transfer across the ferritin protein cage. [Wiki]

Pathways: Transition Metal Ion Homeostasis