HDAC6 antibody

Catalog No. ABIN4953258

This Mouse Monoclonal antibody specifically detects HDAC6 in WB. It exhibits reactivity toward Human.

Quick Overview for HDAC6 antibody (ABIN4953258)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HDAC6 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3B2-F5-G6

Product Details anti-HDAC6 Antibody

Purification: Protein G affinity

Immunogen: A human recombinant protein was used as the immunogen for this HDAC6 antibody.

Isotype: IgG2a

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Storage: -20 °C

Storage Comment: Store the HDAC6 antibody at -20°C.

Target Details for HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Alternative Name: HDAC6

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [UniProt]

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling