ABCG2 antibody (AA 305-335)

Catalog No. ABIN3030062

The Rabbit Polyclonal anti-ABCG2 antibody has been validated for WB, FACS, IF, ELISA and IHC. It is suitable to detect ABCG2 in samples from Human.

Quick Overview for ABCG2 antibody (AA 305-335) (ABIN3030062)

Target: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCG2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)

Product Details anti-ABCG2 Antibody

Binding Specificity: AA 305-335

Purification: Purified

Immunogen: A portion of amino acids 305-335 from the human protein was used as the immunogen for this ABCG2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ABCG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ABCG2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ABCG2

Target: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Alternative Name: ABCG2

Background: ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.

UniProt: Q9UNQ0

Pathways: Transition Metal Ion Homeostasis