CXCR4 antibody (AA 50-79)

Catalog No. ABIN3030512

The Rabbit Polyclonal anti-CXCR4 antibody has been validated for WB and ELISA. It is suitable to detect CXCR4 in samples from Human.

Quick Overview for CXCR4 antibody (AA 50-79) (ABIN3030512)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CXCR4 Antibody

Binding Specificity: AA 50-79

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig, Primate

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 50-79 from the human protein was used as the immunogen for this anti-CXCR4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the anti-CXCR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the anti-CXCR4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4

Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events