c-FOS antibody (AA 263-291)
Quick Overview for c-FOS antibody (AA 263-291) (ABIN3030223)
Target
See all c-FOS (c-Fos) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 263-291
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Cross-Reactivity (Details)
- Expected species reactivity: Bovine, Rat
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Purification
- Purified
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Immunogen
- A portion of amino acids 263-291 from the human protein was used as the immunogen for this c-Fos antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the c-Fos antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the c-Fos antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- c-FOS (c-Fos) (c-Fos)
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Alternative Name
- C-Fos
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Background
- The Fos family consists of 4 members: c-FOS, FOSB, FOSL1, and FOSL2. These leucine zipper proteins can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, these proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the c-Fos gene has also been associated with apoptotic cell death.
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UniProt
- P01100
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Pathways
- S100 Proteins
Target
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