CD68 antibody (AA 209-237)

Catalog No. ABIN3030411

This anti-CD68 antibody is a Rabbit Polyclonal antibody detecting CD68 in WB and ELISA. Suitable for Human.

Quick Overview for CD68 antibody (AA 209-237) (ABIN3030411)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD68 Antibody

Binding Specificity: AA 209-237

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 209-237 from the human protein was used as the immunogen for this CD68 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CD68 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD68 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68

Background: This gene encodes a 40~110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

UniProt: P34810