CD86 antibody (AA 269-298)

Catalog No. ABIN3030429

This anti-CD86 antibody is a Rabbit Polyclonal antibody detecting CD86 in WB and ELISA. Suitable for Human.

Quick Overview for CD86 antibody (AA 269-298) (ABIN3030429)

Target: CD86

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD86 Antibody

Binding Specificity: AA 269-298

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 269-298 from the human protein was used as the immunogen for this CD86 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CD86 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD86 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD86

Target: CD86

Alternative Name: CD86

Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation