CYP26A1 antibody (AA 467-497)

Catalog No. ABIN3030691

This Rabbit Polyclonal antibody specifically detects CYP26A1 in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for CYP26A1 antibody (AA 467-497) (ABIN3030691)

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP26A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CYP26A1 Antibody

Binding Specificity: AA 467-497

Purification: Purified

Immunogen: A portion of amino acids 467-497 from the human protein was used as the immunogen for this CYP26A1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CYP26A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CYP26A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CYP26A1

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Alternative Name: CYP26A1

Background: CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.

UniProt: O43174

Pathways: Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process