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FGFR1 antibody (AA 132-161)

FGFR1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029719
  • Target See all FGFR1 Antibodies
    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
    Binding Specificity
    • 29
    • 26
    • 19
    • 17
    • 17
    • 16
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 132-161
    Reactivity
    • 225
    • 97
    • 93
    • 23
    • 21
    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 216
    • 41
    • 1
    Rabbit
    Clonality
    • 209
    • 49
    Polyclonal
    Conjugate
    • 121
    • 21
    • 18
    • 15
    • 11
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGFR1 antibody is un-conjugated
    Application
    • 222
    • 108
    • 63
    • 57
    • 52
    • 33
    • 24
    • 22
    • 22
    • 15
    • 14
    • 9
    • 7
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 132-161 from the human protein was used as the immunogen for this FGFR antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FGFR1 Primary Antibody
  • Application Notes
    Titration of the FGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the FGFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
    Abstract
    FGFR1 Products
    Background
    FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
    UniProt
    P11362
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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