LIM Domain Kinase 1 antibody (AA 479-508)
Quick Overview for LIM Domain Kinase 1 antibody (AA 479-508) (ABIN3028800)
Target
See all LIM Domain Kinase 1 (LIMK1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 479-508
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Purification
- Purified
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Immunogen
- A portion of amino acids 479-508 from the human protein was used as the immunogen for this LIMK1 antibody.
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Isotype
- IgG1 kappa
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Application Notes
- Titration of the LIMK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the LIMK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- LIM Domain Kinase 1 (LIMK1)
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Alternative Name
- LIMK1
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Background
- Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
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UniProt
- P53667
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
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