WNT3 antibody (AA 155-184)
Quick Overview for WNT3 antibody (AA 155-184) (ABIN3029628)
Target
See all WNT3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 155-184
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Chicken, Xenopus
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 155-184 from the human protein was used as the immunogen for this WNT3 antibody.
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Isotype
- Ig Fraction
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anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (AA 128-355) antibody
WNT3 Reactivity: Human WB, IHC, IHC (p) Host: Mouse Monoclonal 1G7 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (Internal Region) antibodyVerified WNT3 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (AA 128-355) antibodyWNT3 Reactivity: Human WB, IHC, IHC (p) Host: Mouse Monoclonal 1F6 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) antibodyWNT3 Reactivity: Human, Mouse, Rat, Dog WB, ELISA, IHC (p), IF Host: Goat Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (AA 22-355) antibodyWNT3 Reactivity: Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (AA 166-355) antibodyWNT3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (AA 1-355) antibodyWNT3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (AA 143-192) antibodyWNT3 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Bat, Chicken, Monkey, Pig, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (Middle Region) antibodyWNT3 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- Titration of the WNT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the WNT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
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Alternative Name
- WNT3
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Background
- The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
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UniProt
- P56703
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Pathways
- WNT Signaling, Regulation of Cell Size
Target
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