KRT20 antibody

Catalog No. ABIN4956439

This Mouse Monoclonal antibody specifically detects KRT20 in WB, IHC, ELISA and ICC. It exhibits reactivity toward Human.

Quick Overview for KRT20 antibody (ABIN4956439)

Target: KRT20 (Keratin 20 (KRT20))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT20 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: IT-Ks20-10

Product Details anti-KRT20 Antibody

Cross-Reactivity: Pig (Porcine), Human, Rat (Rattus)

Purification: purified

Immunogen: purified keratin K20 from human intestinal mucosa

Isotype: IgG1

Application Details

Application Notes: Dilution for IHC: ready-to-use

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL deionized water

Buffer: PBS, pH 7.93

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Target Details for KRT20

Target: KRT20 (Keratin 20 (KRT20))

Alternative Name: keratin K20

Background: IT-Ks 20.10 represents an excellent marker for certain types of carcinomas such as adenocarcinomas of the colon, transitional cell carcinomas of the bladder and Merkel cell tumors of the skin. Very sensitive detection of intestestinal and gastric foveolar epithelium, urothelial umbrella cells, Merkel cells of epidermis as well as tumors originating therefrom (e.g. primary and metastatic colorectal carcinoma). Adenocarcinomas of breast, lung, endometrium and ovary (non-mucinous) as well as neuroendocrine tumors of the lung are essentially negative. Polypeptide recognized: protein IT (keratin K20, Mr 46 000, formerly also designated cytokeratin 20).

Molecular Weight: Mr 180 000 polypeptide (clathrin heavy chain) from coated vesicles of various tissues