ALDH3A2 antibody (C-Term)

Catalog No. ABIN499265

The Rabbit Polyclonal anti-ALDH3A2 antibody has been validated for WB and EIA. It is suitable to detect ALDH3A2 in samples from Human and Mouse.

Quick Overview for ALDH3A2 antibody (C-Term) (ABIN499265)

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH3A2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ALDH3A2 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to ALDH3A2.

Purification: Affinity chromatography purified via peptide column

Immunogen: Aldh3A2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Aldh3A2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: Aldh3A2 antibody can be used for detection of Aldh3A2 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for ALDH3A2

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Alternative Name: ALDH3A2 / ALDH10

Background: Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism. At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.Synonyms: Aldehyde dehydrogenase 10, Aldehyde dehydrogenase family 3 member A2, FALDH, Fatty aldehyde dehydrogenase, Microsomal aldehyde dehydrogenase

Gene ID: 224

NCBI Accession: NP_001026976

UniProt: P51648