CIDEA antibody (C-Term)

Catalog No. ABIN499625

The Rabbit Polyclonal anti-CIDEA antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect CIDEA in samples from Human.

Quick Overview for CIDEA antibody (C-Term) (ABIN499625)

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIDEA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CIDEA Antibody

Binding Specificity: C-Term

Specificity: CIDE-A antibody was raised against a peptide corresponding to amino acids 200 to 217 of human CIDE-A. It has no cross activity to CIDE-B.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human CIDE-A (C-Terminus) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CIDE-A antibody can be used for detection of CIDE-A at 1/1000 to 1/2000dilution. An approximately 23 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Alternative Name: CIDE-A

Background: Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD (1-4). DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (5). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (5,6). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues.Synonyms: CIDE A, CIDEA, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A

Gene ID: 1149

UniProt: O60543