C1QTNF4 antibody (N-Term)

Catalog No. ABIN499671

This anti-C1QTNF4 antibody is a Rabbit Polyclonal antibody detecting C1QTNF4 in WB, IHC (p) and EIA. Suitable for Human, Mouse and Rat.

Quick Overview for C1QTNF4 antibody (N-Term) (ABIN499671)

Target: C1QTNF4 (Complement C1q Tumor Necrosis Factor-Related Protein 4 (C1QTNF4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QTNF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-C1QTNF4 Antibody

Binding Specificity: N-Term

Specificity: CTRP4 antibody was raised against a 16 amino acid peptide from near the center of human CTRP4.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human CTRP4 (N-Terminus) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CTRP4 antibody can be used for the detection of CTRP4 at 1 - 2 μg/mL. Ratbrain cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for C1QTNF4

Target: C1QTNF4 (Complement C1q Tumor Necrosis Factor-Related Protein 4 (C1QTNF4))

Alternative Name: C1QTNF4

Background: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of mouse CTRP4 have been reported.Synonyms: CTRP4, Complement C1q tumor necrosis factor-related protein 4

Gene ID: 114900

UniProt: Q9BXJ3