CTRP6 antibody (Intermediate Domain)

Catalog No. ABIN499679

The Rabbit Polyclonal anti-CTRP6 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect CTRP6 in samples from Human, Mouse and Rat.

Quick Overview for CTRP6 antibody (Intermediate Domain) (ABIN499679)

Target: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTRP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CTRP6 Antibody

Binding Specificity: Intermediate Domain

Specificity: CTRP6 antibody was raised against a 15 amino acid peptide from near the center of human CTRP6.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human CTRP6 (Intermediate Domain) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CTRP6 antibody can be used for the detection of CTRP6 at 1 μg/mL. Mousebrain cell lysate can be used as positive control. These proteins often migrate in SDS-PAGEat positions other than their predicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CTRP6

Target: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Alternative Name: C1QTNF6

Background: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). CTRP6 contains at least 4 glycosylation motifs, suggesting that CTRP6 may be highly post-translationally modified (3).Synonyms: CTRP6, Complement C1q tumor necrosis factor-related protein 6

Gene ID: 114904

UniProt: Q9BXI9