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GRTP1 antibody (N-Term)

The Rabbit Polyclonal anti-GRTP1 antibody has been validated for WB, IF and EIA. It is suitable to detect GRTP1 in samples from Human, Mouse and Rat.
Catalog No. ABIN499934

Quick Overview for GRTP1 antibody (N-Term) (ABIN499934)

Target

See all GRTP1 Antibodies
GRTP1 (Growth Hormone Regulated TBC Protein 1 (GRTP1))

Reactivity

Human, Mouse, Rat

Host

  • 16
Rabbit

Clonality

  • 16
Polyclonal

Conjugate

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRTP1 antibody is un-conjugated

Application

  • 9
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term

    Purification

    Affinity chromatography purified via peptide column

    Immunogen

    GRTP1 antibody was raised against a 18 amino acid peptide from near the amino terminus of human GRTP1.

    Isotype

    IgG
  • Application Notes

    ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C.
  • Target

    GRTP1 (Growth Hormone Regulated TBC Protein 1 (GRTP1))

    Alternative Name

    GRTP1 / TBC1D6

    Background

    Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist, this antibody should recognize all isoforms.Synonyms: Growth hormone-regulated TBC protein 1, TBC1 domain family member 6

    Gene ID

    79774

    UniProt

    Q5TC63
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