CSMD2 antibody (AA 251-350) (AbBy Fluor® 750)

Catalog No. ABIN5000614

The Rabbit Polyclonal anti-CSMD2 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect CSMD2 in samples from Mouse.

Quick Overview for CSMD2 antibody (AA 251-350) (AbBy Fluor® 750) (ABIN5000614)

Target: CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSMD2 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CSMD2 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 251-350

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSMD2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CSMD2

Target: CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

Alternative Name: CSMD2

Background:

Synonyms: CSMD2, CSMD2_HUMAN, CUB and Sushi SCR repeat domain, CUB and sushi domain-containing protein 2, CUB and sushi multiple domains protein 2, dJ1007G16.1, dJ1007G16.2, dJ947L8.1, KIAA1884.

Background: The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.

Gene ID: 114784