DNAJC7 antibody (AA 221-320) (AbBy Fluor® 750)

Catalog No. ABIN5001387

This Rabbit Polyclonal antibody specifically detects DNAJC7 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DNAJC7 antibody (AA 221-320) (AbBy Fluor® 750) (ABIN5001387)

Target: DNAJC7 (DnaJ (Hsp40) Homolog, Subfamily C, Member 7 (DNAJC7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJC7 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DNAJC7 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 221-320

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNAJC7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DNAJC7

Target: DNAJC7 (DnaJ (Hsp40) Homolog, Subfamily C, Member 7 (DNAJC7))

Alternative Name: DNAJC7

Background:

Synonyms: DnaJ homolog subfamily C member 7, Tetratricopeptide repeat protein 2, TPR repeat protein 2, TPR2, TTC2, DNJC7_HUMAN.

Background: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are in-volved in the regulation of protein degradation, exocytsis and endocytosis. DnaJC7 (DnaJ homolog subfamily C member 7), also known as TPR2, TTC2 or DANJC7, is ubiquitously expressed, with highest expression in testis, liver, heart and brain.

Gene ID: 7266

UniProt: Q99615