DOK3 antibody (AA 45-145) (AbBy Fluor® 750)

Catalog No. ABIN5001445

The Rabbit Polyclonal anti-DOK3 antibody has been validated for WB, IF (cc), IF (p). It is suitable to detect DOK3 in samples from Mouse.

Quick Overview for DOK3 antibody (AA 45-145) (AbBy Fluor® 750) (ABIN5001445)

Target: DOK3 (Docking Protein 3 (DOK3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK3 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DOK3 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 45-145

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOK3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DOK3

Target: DOK3 (Docking Protein 3 (DOK3))

Alternative Name: DOK3

Background:

Synonyms: Docking protein 3, DOK 3, DOK Like Protein, DOKL Pending, Downstream of tyrosine kinase 3, p62 DOK Like Protein, DOK3_HUMAN.

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl functionDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function. There are 4 isoforms generated by alternative splicing.

Gene ID: 79930