S1PR4 antibody (AA 301-384) (AbBy Fluor® 750)

Catalog No. ABIN5001735

This Rabbit Polyclonal antibody specifically detects S1PR4 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for S1PR4 antibody (AA 301-384) (AbBy Fluor® 750) (ABIN5001735)

Target: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR4 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-S1PR4 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 301-384

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDG6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for S1PR4

Target: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Alternative Name: EDG6

Background:

Synonyms: Endothelial dferentiation lysophosphatidic acid G protein coupled receptor 6, Endothelial dferentiation G protein coupled receptor 6, Endothelial dferentiation gene 6, LPC1, Lysophospholipid receptor C1, MGC129298, Putative G protein coupled receptor, S1P receptor 4, S1P receptor Edg6, S1P4, S1PR4, SLP4, Sphingosine 1 phosphate receptor 4, Sphingosine 1 phosphate receptor Edg6, S1PR4_HUMAN.

Background: This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.

Gene ID: 8698