CLEC14A antibody (AA 260-310) (AbBy Fluor® 680)

Catalog No. ABIN5001834

This Rabbit Polyclonal antibody specifically detects CLEC14A in WB and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CLEC14A antibody (AA 260-310) (AbBy Fluor® 680) (ABIN5001834)

Target: CLEC14A (C-Type Lectin Domain Family 14, Member A (CLEC14A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC14A antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CLEC14A Antibody (AbBy Fluor® 680)

Binding Specificity: AA 260-310

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EGFR5/CLEC14A

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CLEC14A

Target: CLEC14A (C-Type Lectin Domain Family 14, Member A (CLEC14A))

Alternative Name: EGFR5

Background:

Synonyms: CEG1, EGFR-5, C14orf27, C-type lectin domain family 14 member A, Epidermal growth factor receptor 5, CLEC14A, EGFR5, UNQ236/PRO269

Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.

Gene ID: 161198

UniProt: Q86T13