GNRPX antibody (AA 1-100) (AbBy Fluor® 750)

Catalog No. ABIN5003750

This anti-GNRPX antibody is a Rabbit Polyclonal antibody detecting GNRPX in IF (cc) and IF (p). Suitable for Human.

Quick Overview for GNRPX antibody (AA 1-100) (AbBy Fluor® 750) (ABIN5003750)

Target: GNRPX (PLEKHJ1) (Pleckstrin Homology Domain Containing, Family J Member 1 (PLEKHJ1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNRPX antibody is conjugated to AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GNRPX Antibody (AbBy Fluor® 750)

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNRPX/PLEKHJ1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GNRPX

Target: GNRPX (PLEKHJ1) (Pleckstrin Homology Domain Containing, Family J Member 1 (PLEKHJ1))

Alternative Name: GNRPX

Background:

Synonyms: Guanine nucleotide releasing protein x, Guanine nucleotide-releasing protein x, Likely ortholog of mouse guanine nucleotide releasing protein x, PH domain containing family J member 1, PH domain-containing family J member 1, PKHJ1_HUMAN, Pleckstrin homology domain containing family J member 1, Pleckstrin homology domain-containing family J member 1, PLEKHJ 1, PLEKHJ1, 9530063M10Rik, FLJ10297.

Background: PLEKHJ1 is a 149 amino acid phosphoprotein that contains one PH (pleckstrin homology) domain and is expressed in testis and liver. The gene that encodes PLEKHJ1 maps to human chromosome 19, which consists of approximately 63 million bases and makes up over 2 % of human genomic DNA. Chromosome 19 contains the greatest gene density of the human chromosomes and is the genetic home for a number of immunoglobulin superfamily members, including killer cell and leukocyte Ig-like receptors, ICAMs, the CEACAM and PSG families, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes are also linked to chromosome 19.

Gene ID: 55111